Queensland has recorded 765 new cases of COVID-19 on Christmas Day from more than 33,000 tests.
Health Minister Yvette D'Ath said the state had been "preparing for a year" for the cases, adding hospitalisations remain low.
There are 2147 people with the virus in the state, and 151 have been confirmed as the new Omicron strain.
"There are definitely more cases, but because of the great work of Queenslanders coming out and getting vaccinated, our hospitalisation rates still remain very low," she said.
Five people are in hospital due to COVID-19, though the single person in ICU earlier this week has now been moved out.
There are other people with COVID-19 in hospital, but not due to the virus.
There are 566 people with the virus getting care at home.
The Health Minister tweeted a warning, saying "Most Queenslanders don't know someone who has had COVID-19, in the coming days and months they will."
A total of 90.3 per cent of Queenslanders have had their first vaccination and 88.5 have had both.
She said 650 people were 'formally' in quarantine, which was lower than recently due to changed close contact rules.
More to come…